Protease inhibitors from Ascaris lumbricoides

Ascaris Lumbricoides

Protocollagen proline hydroxylase from Ascaris lumbricoides.

An enzyme was found in the muscle layers of Ascaris lumbricoides which was similar to the protocollagen proline hydroxylase found in chick embryos and other vertebrates in that it synthesized 14C-hydroxyprolme when incubated with 14C-proline-labeled protocollagen from chick cartilage. The Ascaris enzyme was also similar in that it required atmospheric oxygen, a-ketoglutarate, iron, and ascorbat...

Ascaris lumbricoides--the ubiquitous roundworm.

Ascaris lumbricoides: a case report.

This is a case presentation of a multiple trauma patient who was infested with Ascaris lumbricoides, a roundworm. The infestation was undiagnosed until after extubation. Intraoperative anesthesia was uneventful and the patient was discharged 7 days after admission.

Structural Basis for the Immunomodulatory Function of Cysteine Protease Inhibitor from Human Roundworm Ascaris lumbricoides

Immunosuppression associated with infections of nematode parasites has been documented. Cysteine protease inhibitor (CPI) released by the nematode parasites is identified as one of the major modulators of host immune response. In this report, we demonstrated that the recombinant CPI protein of Ascaris lumbricoides (Al-CPI) strongly inhibited the activities of cathepsin L, C, S, and showed weake...